"how to heal a sprained ankle overnight" While it's not possible to fully heal a sprained ankle overnight, you can take steps to promote healing and reduce discomfort. Initially, it's important to rest and avoid putting weight on the affected ankle. Applying ice packs wrapped in a cloth for 15-20 minutes at a time, several times a day, can help reduce swelling. Compressing the ankle with a bandage and elevating it above heart level can also aid in reducing inflammation. Over-the-counter pain relievers may provide temporary relief. However, it's recommended to consult with a healthcare professional for proper diagnosis, treatment recommendations, and a realistic timeline for recovery.